Features of Eye Endran

• Various PN skin boosters are currently introduced in the market. Eye Endran has a similar PN content and ingredient composition to existing well-known PN products. It is particularly important to confirm that the PN ingredient is extracted from salmon. This can be a suitable choice for those who need consistent management at a reasonable cost.
• This is a personalized treatment that adjusts the treatment area and skin layer depth from under the eyes to the eyelids and the periorbital area.
• A precise amount of 2cc of PN ingredient is injected as is, without dilution.
• Its low viscosity reduces discomfort during treatment, and post-treatment swelling (embossing) can also disappear relatively quickly.
• Developed specifically for the delicate eye area, it can be considered for stable treatment even on sensitive skin.
• Since there is less discomfort during eye area treatment, full-face treatment is also possible. It can help improve overall skin dullness, dryness, and fine wrinkles.
• Precise treatment is performed with the expertise of experienced medical staff in dermal layer injection. After the treatment, we confirm the eye area swelling (embossing) with the patient.

Understanding Eye Endran (PN) Skin Booster

Eye Endran is a skin booster composed of PN (Polynucleotide) ingredients, specifically designed for the delicate skin around the eyes.

It is a delicate treatment that can be used to improve fine wrinkles, dark circles, and dryness around the eyes.

While its ingredients and content are similar to certain PN fillers, it is developed for thin skin like the eye area, providing a smooth injection sensation. This can lead to less pain, and post-treatment swelling (embossing) also tends to subside more quickly.

Why Eye Endran is Needed for the Eye Area

The skin around the eyes is much thinner and more delicate compared to other areas of the face.

Due to these characteristics, it is vulnerable to external stimuli, and changes due to aging or dryness can appear quickly.

The skin barrier easily weakens, often leading to dryness, fine wrinkles, and bluish dark circles.

The eye area has little subcutaneous fat and a thin dermal layer, limiting the effectiveness of general moisturizers or eye creams.

Therefore, directly injecting PN into the dermal layer to aid skin regeneration can be an effective method for eye area skin care.

What is the PN (Polynucleotide) ingredient?

PN is a high-purity, biocompatible substance extracted from salmon DNA.

It has a larger molecular weight compared to the widely known PDRN, and it can be expected to induce a longer-lasting response and effect in the skin's dermal layer.

Simply put, while PDRN primarily aids basic hydration and regeneration, PN can contribute to inducing changes in skin structure by stimulating the dermal layer.

PN can help improve skin through several processes.

It stimulates fibroblasts to help produce collagen and elastin. This can contribute to adding elasticity to the skin, alleviating fine wrinkles, and making the skin texture smoother.

It promotes the secretion of growth factors such as TGF, FGF, and VEGF. This aids in the skin's recovery process and supports the regeneration of damaged tissues. Additionally, it can contribute to maintaining healthy skin by alleviating inflammatory responses.

It induces the regeneration of epidermal cells and strengthens the skin barrier. This can help improve internal skin dryness by strengthening the bonds between keratinocytes and reducing moisture loss.

The skin has a barrier structure composed of bricks (keratinocytes) and cement (intercellular lipids).

PN can help restore this cement-like function, suppressing moisture evaporation and improving skin sensitivity along with internal dryness.

It induces the recovery of damaged dermal tissue and an increase in thickness. As the thinned dermis thickens, it can contribute to the alleviation of dark circles and the improvement of fine wrinkles.

The skin barrier is composed of brick-like keratinocytes and intercellular lipids that act as cement connecting them. PN can help restore this cement-like function, preventing skin moisture loss to reduce internal dryness and improve sensitivity.

Embossing Phenomenon and the Importance of Dermal Layer Injection

Anatomically, the dermal layer has very limited space.

When a substance is injected here, a temporary swelling phenomenon may occur.

This is called the embossing phenomenon, and it can be an indicator that the substance has been properly delivered to the target dermal layer.

At our clinic, we personally confirm and explain the post-treatment embossing phenomenon with the patient.

While other PN products typically show embossing lasting 3 to 7 days or more, Eye Endran has a low viscosity, so it is quickly absorbed, mostly within 1 week. Additionally, discomfort is relatively low, allowing for comfortable treatment even in delicate areas like the eyes.

Recommended for these individuals

• Those who are starting to notice fine wrinkles around their eyes.
• Recommended for those concerned about bluish dark circles. The bluish appearance around the eyes is due to thin dermis allowing blood vessels to show through. Eye Endran can subtly reinforce dermal thickness, helping to alleviate dark circles.
• Those whose makeup flakes or skin texture becomes rough due to internal skin dryness.
• This treatment can be recommended for those who are cautious about lifting procedures due to thin and sensitive skin.
• This procedure is for those who feel that eye cream alone is not enough for their eye area skin care.
• Even those who are concerned about fine wrinkles on their eyelids but have been told that treatment is difficult elsewhere can expect improvement after consultation.
• We can help those who are bothered by fine wrinkles around the eyes.

Treatment Interval and Duration

• Typically, we recommend 3 sessions at one-month intervals.
• Receiving touch-ups every 6 months thereafter can help maintain the treatment effect.
• The duration of the treatment effect varies from person to person, but can generally be expected to last approximately 6 months to 1 year.
• Pain during the procedure is generally less than with existing Rejuran, and swelling at the treated area usually subsides naturally within 1 to 3 days.

Doctor's Insights

I believe that eye area treatments should not merely focus on wrinkle improvement, but rather on activating the skin's inherent regenerative and recuperative abilities.

A single session of Eye Endran treatment can likely have a more positive impact on skin changes than consistently using eye cream.

There are times when general skincare products alone are not enough to adequately address concerns about the skin around the eyes.

In such cases, it is necessary to improve the internal skin environment. Procedures that supplement the density and thickness of the dermal layer fall into this category.

Eye Endran can be one method for this approach.

Just as much as we strive for skin improvement, the treatment process itself must be meticulous and honest.

Alongside precise injection techniques, thorough pre- and post-treatment checks, and ensuring patients' comfort throughout the process are all crucial.

Our medical team is committed to accompanying our patients through every step of this journey.