Features of Endran Healer

1. Same Main Ingredient, More Reasonable Cost

By utilizing salmon-derived PN ingredients, similar to Rejuran, you can expect comparable effects while reducing the cost burden.

2. Planned Approach, Precise Procedure

We inject PN ingredients by understanding the anatomical structure of the skin and considering the depth of each layer. This allows us to expect better results.

3. Injection Confirmation through Wheal Formation

Immediately after the procedure, we confirm the wheal formation on the skin with the patient to ensure that the medication has reached the intended area.

4. Consultation and Procedure Directly Performed by the Director

After thoroughly assessing the patient's skin condition and previous treatment history, we proceed with a customized procedure suitable for each individual.

5. Management to Reduce Irritation and Aid Comfortable Recovery

After the procedure, we use a Jaungo modeling mask to soothe sensitive skin and help with the recovery process.

6. Adjustment of Wheal Spacing Depending on the Area

For the cheeks and forehead, the injection spacing is adjusted to maximize efficacy, while for the eye and mouth areas, a more delicate and precise spacing is used. We consider a combination of factors such as skin thickness, elasticity, and wrinkle direction to adjust the treatment intervals. This goes beyond simply injecting a set amount; it's a personalized approach tailored to individual skin characteristics.

Considerations for Endran Healer Procedure

1. Same Key Ingredient, Reasonable Consideration

As the patent for PN (Polynucleotide) ingredients in existing products has expired, various products based on the same salmon-derived PN are now being introduced.

Endran Healer also contains these same ingredients,

allowing for consideration of the procedure at a more reasonable cost.

If you are looking for a practical PN-based treatment approach that offers similar improvement effects while reducing the financial burden,

Endran Healer could be an option for you.

2. Important Treatment Method Alongside Ingredients

Just because PN ingredients are included doesn't mean all procedures will yield the same results.

The Endran Healer procedure is not simply about injecting medication;

it involves a meticulous consideration of the exact skin layer, appropriate depth, and necessary amount for injection.

We meticulously diagnose skin thickness, degree of damage, and pore structure to adjust the depth of the procedure to suit each skin layer.

This approach can contribute to dermal layer remodeling and collagen regeneration.

3. Confirmation of Treatment Location through Wheal Formation

Whether PN ingredients have been precisely injected into the skin

is confirmed visually by both the medical staff and the patient immediately after the procedure.

The wheal formation that appears after the procedure is not merely a temporary reaction but can serve as an indicator that the medication has successfully reached the targeted dermal layer.

After the procedure, we confirm and explain the wheal formation to the patient.

We believe that a brief confirmation of wheal formation can positively influence the outcome of the procedure.

4. 1:1 Consultation and Procedure Personally Led by the Director

Instead of a typical explanation by a consultation manager,

the patient's skin condition, sensitivity, past treatment experiences, currently used products, etc., are

personally and carefully assessed by the director from start to finish.

This process allows PN ingredients to work more effectively,

and can also help prevent potential side effects or unnecessary inflammatory reactions.

5. Management to Reduce Skin Irritation and Aid Recovery

For skin soothing after PN procedures, we basically include and provide a Jaungo modeling mask.

When heat, redness, or skin sensitivity reactions occur, we comfort your skin through a complex traditional Korean medicine soothing management.

This can help to pre-regulate the occurrence of excessive immune reactions in the skin.

Therefore, even thin or sensitive skin types can consider PN treatment.

At our clinic, we also consider the recovery process after treatment important and focus on overall management.

6. Customized plan for embos spacing by treatment area

When performing Endran Filler treatment, we proceed with careful consideration of the injection locations as well as the spacing between each injection point.

For example, in areas like the cheeks or forehead where the dermis layer is relatively thick and wide,

even if the PN component is injected into just one point, it can widely diffuse to the surrounding area, allowing for expected improvement effects with 1~1.5cm spacing.

In contrast, for areas where skin tissue is thin and wrinkles are concentrated, such as around the eyes or mouth,

precise injection at 0.5cm intervals is necessary to expect skin texture improvement.

If the skin is thin and has many sunken areas, or

if the skin texture structure has become irregular due to laser treatment or similar procedures, a more dense injection interval can be considered even for the cheeks or forehead.

At our clinic, we comprehensively consider skin thickness, elasticity, wrinkle direction, and treatment goals to

plan and apply the location of the embos and injection intervals in a way that is tailored to each individual patient.

This means that even with the same volume (e.g., 2cc, 4cc), the impact on treatment results can vary.

This personalized approach, considering each individual's condition, can be seen as one of Endran Filler's important advantages.

What are the Expected Effects of Endran Filler?

1. Expectation of skin structure improvement by promoting collagen and elastin production

The PN (Polynucleotide) component extracted from salmon stimulates fibroblasts in the skin's dermis layer,

aiding in the synthesis of collagen and elastin.

As a result, a gradual increase in skin thickness, reduction in fine wrinkles, and improved elasticity can be expected.

In addition, improvement in pore condition can also be expected.

2. Helps restore damaged skin barrier and enhance skin self-regeneration

The PN component induces the secretion of growth factors such as TGF and FGF, helping epidermal cell regeneration and contributing to the recovery of the skin barrier.

This can positively impact the alleviation of inner skin dryness, improvement of sensitivity, and overall enhancement of skin recovery.

It can be particularly helpful in facilitating the recovery process of skin sensitized after laser treatments or peelings.

3. Natural Improvement of Skin Condition

Endran Filler does not work by injecting immediate volume like fillers, or by relaxing muscles like Botox.

Instead, it restores the skin's natural vitality, leading to smoother skin texture and relief from inner skin tightness. Furthermore, improved makeup adherence can also be expected.

If you desire healthy changes within your skin rather than significant external alterations, Endran Filler can be an option.

Principle of Endran Filler Action

1. Skin Structure Improvement through Fibroblast Activation

The main component of Endran Filler, PN (Polynucleotide),

is a high-purity DNA fragment extracted from salmon, which, when injected into the skin,

can be recognized as a signal for damaged skin, promoting the activity of fibroblasts.

These fibroblasts play a role in helping to produce skin components such as collagen, elastin, and hyaluronic acid.

This contributes to improving skin structure, making it stronger and more elastic.

2. Enhancement of Skin Self-Regenerative Capacity through Growth Factor Secretion

Activated fibroblasts are involved in secreting various growth factors crucial for skin regeneration.

TGF-β: Plays a role in aiding collagen synthesis.

FGF helps in the regeneration of skin cells and tissue repair.

VEGF contributes to nutrient supply by promoting smooth circulation in the skin's microvessels.

These growth factors create an environment where the skin can regenerate itself.

This naturally helps to restore damaged epidermis and skin barrier function.

As a result, skin sensitivity can be reduced, inner dryness can be alleviated, and overall recovery power can be improved.

3. You can expect a feeling of fuller skin due to improved dermal density.

Endran Hiller directly acts on the dermis, a crucial structure that supports the skin.

The PN component helps to remodel the extracellular matrix (ECM) components such as collagen, elastin, and hyaluronic acid that make up the dermis.

This helps to densely refill the dermal tissue with important substances such as collagen, hyaluronic acid, and proteins.

As a result, the skin's internal elasticity improves, making it firmer. This also positively affects the reduction of sunken areas and refines skin texture, leading to skin that absorbs makeup better.

4. It minimizes irritation, promotes rapid recovery, and is involved in anti-inflammatory action.

PN is an ingredient that contributes to regulating micro-inflammatory reactions within the skin, along with promoting skin regeneration.

Chronic redness

Skin that reacts sensitively to external stimuli

Sensitive reactions appearing after laser procedures

In these various skin conditions, it can help alleviate inflammatory reactions and promote a healthy recovery process.

Therefore, Endran Hiller is one of the PN treatments that even individuals with sensitive or delicate skin can relatively safely consider.

Endran Hiller Treatment Procedure

1. Precise Skin Diagnosis

Before the procedure, we meticulously analyze the patient's skin thickness, elasticity, and sensitivity.

Based on this, a customized plan for the depth and method of PN injection will be established.

2. Director's Individual Consultation

We identify the areas requiring skin improvement and the scope of the treatment,

The director in charge personally conducts a thorough diagnosis and establishes the treatment plan.

We create a customized treatment plan considering each individual's skin characteristics.

3. Anesthetic Cream Application

Since the PN component is injected directly into the dermal layer,

We allow sufficient numbing time, approximately 20 to 30 minutes.

This is to minimize any discomfort that may occur during the procedure.

4. Endran Hiller Injection Procedure

According to the pre-established plan, PN is carefully injected at the precise depth and location.

The injection location is verified in real-time through the appearance of an 'embossing' effect during the procedure,

and if necessary, immediate fine adjustments can be made to enhance the accuracy of the treatment.

5. Jaungo Modeling Pack Post-Care

Immediately after the procedure, a Jaungo modeling pack is used to

help effectively alleviate skin irritation, redness, and heat sensation caused by the injection.

This process prevents unnecessary immune reactions and helps the skin recover stably.

Endran Hiller Treatment Recommended Cycle and Duration of Effect

1. Initial Intensive Management (Generally 3 sessions)

Generally, we recommend receiving a total of 3 sessions at 1-month intervals.

There's a clear reason behind this.

Only when the polynucleotide (PN) component reaches the dermis in the appropriate amount and settles,

can the fibroblasts within the skin be actively stimulated to begin functioning,

and can we expect the stable formation of new collagen.

2. Maintenance Treatments

If you wish to maintain the treatment effects for longer,

you may consider supplemental treatments every 6 months to 1 year.

While the duration of maintenance may vary depending on individual skin condition and lifestyle habits,

generally, after completing all 3 sessions, the effects can be maintained for approximately 6 to 12 months.

3. How long do the effects last?

After the collagen regeneration process within the skin is sufficiently completed,

you can experience improvements in skin texture, elasticity, and density for an average of 6 months or more.

However, in the following cases, the duration of treatment effectiveness may be somewhat shortened:

When the skin is excessively thin or already significantly damaged.

If there are lifestyle habits that negatively affect skin health, such as smoking or excessive UV exposure.

4. When can I expect to see the treatment effects?

Immediately after the procedure, you may experience an embossing effect from the injection or slight swelling.

Approximately 1 week after the procedure, you can feel improved makeup adherence and a gradual refinement of skin texture.

In weeks 2-3, you can expect improved skin elasticity, increased density, and a reduction in fine wrinkles.

After completing all 3 treatment sessions, changes in the internal skin structure become more pronounced, and you can feel an overall improvement in your skin.

How much pain is involved with EndranHeller treatment?

While it varies by individual, most people experience a tolerable stinging sensation.

Since polynucleotide (PN) components are directly injected into the dermal layer of the skin, it cannot be said to be completely painless.

However, because a sufficient numbing process is performed before the treatment, most patients can receive the procedure without significant discomfort.

Differences in Pain by Treatment Area

Areas such as the cheeks, forehead, and around the mouth often experience little to no pain.

The eye area, bridge of the nose, and chin may have a momentary stinging sensation.

Areas with larger pores may feel a dull pressure.

Treatment Process for Pain Reduction

Numbing cream is applied for a sufficient amount of time to stabilize the skin surface.

During the procedure, the medication is injected very slowly and carefully in small amounts.

The patient's condition is monitored in real-time, and pain levels are checked.

After the treatment, post-care, including a soothing pack, is provided to reduce skin discomfort.

Those who need EndranHeller treatment

1. When fine wrinkles have become noticeably abundant

This is for individuals concerned about dense fine wrinkles on their face, such as around the eyes, cheeks, and mouth.

It may be suitable for those who feel burdened by lifting procedures or fillers but desire natural wrinkle improvement.

2. When skin is sensitive and tends to redden frequently

It can help skin that reacts sensitively to cosmetic changes or experiences easily reddening flushing symptoms.

It is also a treatment worth considering for those who wish to strengthen weakened skin barriers and restore the skin's natural health.

3. Those who experience inner skin tightness and poor makeup adherence

Those whose skin appears oily on the surface but feels dry and tight underneath, and whose makeup tends to lift easily

Those who feel deep skin dehydration that cannot be resolved with typical moisturizing alone

4. Those whose skin has accumulated fatigue due to frequent procedures

Those whose skin has become sensitive or thin after multiple laser or peeling treatments

When you want to restore your skin's natural healthy condition

5. Those who desire improved skin density and texture refinement

When skin elasticity has decreased, causing the skin to feel sagging and spread out

Those who feel their cheekbones or cheeks have lost elasticity and sag, and believe their skin texture is uneven

Endran Hiller Treatment: Post-Procedure Bumps (Embossing)

Immediately after Endran Hiller treatment, raised bumps or 'embossing' may appear at the injection sites.

These bumps also indicate that the medication has been properly injected into the dermal layer of the skin.

The appearance of small raised areas on the skin is a normal reaction and can be interpreted as a positive sign of the treatment's effectiveness.

Generally, these bumps tend to subside naturally within 1-2 days.

However, for individuals with thin or dry skin, the bumps might persist for 2-3 days, and up to 4 days in sensitive areas like around the eyes or mouth.

Occasionally, bumps may remain for 5-7 days or longer,

but if there are no symptoms such as pain, warmth, or excessive redness, there is no need to worry.

In fact, it could be a positive sign that the treatment solution is being absorbed slowly, allowing it to act on the skin for a longer period.

Post-Treatment Precautions

• ✔ The unevenness, redness, and slight pain at the injection sites after treatment may persist for about 2-3 days.
• ✔ Please be aware that bruising, needle marks, and swelling may last for about 1-2 weeks after the procedure.
• ✔ We recommend refraining from alcohol consumption, smoking, saunas, swimming pool access, and strenuous exercise for about 7 days, as these can irritate the treated area.
• ✔ After the treatment, consistently focus on moisturizing care to soothe your skin, and it is advisable to apply sunscreen thoroughly when going out.